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Brain Cancer treatment details. Chemotherapy. Surgery. University of Kentucky Medical Center , Lexington, Kentucky , United States



Survival: 6.0 months
   
Toxicity Grade:
   
Treatments: Chemotherapy
Surgery
   
Drugs: Blenoxane
Country: United States
   
City/State/Province: Lexington, Kentucky
   
Hospital: University of Kentucky Medical Center
   
Journal: Link
   
Date: 10/2002

Description:
Patients: This Phase I study involved 9 patients with recurrent glioblastoma multiforme.

Treatment: Treatment consisted of escalating doses of intratumoral bleomycin (blenoxane). The chemotherapy drug bleomycin (blenoxane) was introduced directly into the brain using a modified Ommaya reservoir.

Toxicity: Toxicities included: headaches, somnolence, seizures, skin ulcers, and lethargy. Toxicity grades were not discussed.

Results: The median survival was 6.0 months.

Correspondence: Roy A. Patchell, MD

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