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Rectal Cancer treatment details. Chemotherapy. Radiation. Centre Antoine-Lacassagne, Nice, France

Survival: ?
Toxicity Grade: 4
Treatments: Chemotherapy
Drugs: Adrucil
Country: France
City/State/Province: Nice
Hospital: Centre Antoine-Lacassagne
Journal: Link
Date: 12/2005

Patients: This Phase I study involved 43 patients with locally advanced or metastatic rectal cancer. Thirty-four patients were men, nine were women, and the median age was 59 years.

Treatment: The treatment consisted of radiotherapy and two chemotherapeutic agents: fluorouracil and oxaliplatin.

Toxicity: Grade 3-4 toxicities included anemia, thrombocytopenia, diarrhea, urinary tract toxicity, and asthenia.

Results: The median overall survival was not reported. Two complete responses and 19 partial responses were observed.

Support: Sanofi-Synthelabo financially supported this study. Sanofi-Synthelabo manufactures and/or markets oxaliplatin.

Correspondence: Eric Francois, MD

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