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Rectal Cancer treatment details. Chemotherapy. Radiation. Mount Vernon Cancer Centre, London, United Kingdom

Survival: ?
Toxicity Grade: 4
Treatments: Chemotherapy
Drugs: Eloxatin
Country: United Kingdom
City/State/Province: London
Hospital: Mount Vernon Cancer Centre
Journal: Link
Date: 1/2006

Patients: This Phase I study involved 18 patients with locally advanced rectal cancer. Twelve patients were men, six were women, and the median age was 56.8 years.

Treatment: The treatment consisted of radiation therapy and two chemotherapeutic agents: capecitabine and oxaliplatin.

Toxicity: Grade 1-4 toxicities included diarrhea, lethargy, abdominal pain, and rectal pain.

Results: The median overall survival was not reported. Five patients had a complete response to treatment.

Support: Roche Laboratories provided "study support." Roche markets and/or manufactures capecitabine.

Correspondence: Antonius A. Miller

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