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Prostate Cancer treatment details. Biologic therapy. Weill Medical College of Cornell University, New York, N.Y., United States



Survival: ?
   
Toxicity Grade: 4
   
Treatments: Biologic therapy
   
Drugs:
Country: United States
   
City/State/Province: New York, N.Y.
   
Hospital: Weill Medical College of Cornell University
   
Journal: Link
   
Date: 7/2005

Description:
Patients: This Phase I study involved 35 men with hormone-refractory protstate cancer. The median age was 69 years.

Treatment: The treatment consisted of one biological agent: J591, an isotope-labeled monoclonal antibody that recognizes the prostate specific antigen that is expressed in tumor cells.

Toxicity: Grade 3-4 toxicities included neutropenia, thrombocytopenia, and elevated liver enzymes.

Results: The median overall survival was not reported. The authors were encouraged with the antibody's relatively low toxicity and ability to target tumor tissue.

Correspondence: Neil H. Bander, M.D.

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