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Ovarian Cancer treatment details. Biologic therapy. Immunotherapy. Vancover Cancer Center, Vancouver, Canada

Survival: 8.5 months
Toxicity Grade: 3
Treatments: Biologic therapy
Country: Canada
City/State/Province: Vancouver
Hospital: Vancover Cancer Center
Journal: Link
Date: 11/2005

Patients: This pilot phase II study involved thirteen women with a mean age of 59.1 with recurrent stage III or IV ovarian cancer. Those enrolled in the study had an average of 2.5 prior chemotherapy treatments with a median time from primary chemotherapy treatment of 2.5 months.

Treatment: Patients received two to nine doses of orgovomab (a monoclonal antibody that is directed against a well known ovarian cancer marker that is elevated in nearly all patients with late stage ovarian cancer).

Toxicity: Grade 3 backpain, chills, rash and headache.

Results: There were no complete or partial responses to this treatment and median survival was 8.5 months.

Correspondence: Thomas G. Ehlen, M.D.

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