Cancer Treatment Results  Survival Rates Cancer Treatments / Therapy Results
Cancer
 

Click here to go back to your search results.

Melanoma treatment details. Chemotherapy. Immunotherapy. Istituto Nazionale per lo Studio e la Curra dei Tumori, Milan, Italy



Survival: 11.0 months
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
Immunotherapy
   
Drugs: DTIC-Dome
Platinol
Country: Italy
   
City/State/Province: Milan
   
Hospital: Istituto Nazionale per lo Studio e la Curra dei Tumori
   
Journal: Link
   
Date: 2/2006

Description:
Patients: This phase III study involved 151 patients with metastatic melanoma. Patients were divided into two groups: Group A had 75 patients and Group B had 76 patients. The median age for Group A was 51.5 and the median age for Group B was 46.5.

Treatment: For both groups, patients received chemotherapy (cisplatin, vindesine, decarbazine). In addition, patients in Group B received immunotherapy (interleukin-2 and interferon-alpha2b).

Toxicity: For both groups toxicities included: grade 3/4 fever, anemia, asthenia/fatigue, nausea and neutropenia.

Results: For Group A (chemotherapy only) the overall median survival was 12 months. For Group B (chemotherapy plus immunotherapy) the overall median survival was 11 months. The authors concluded that the addition of immunotherapy is not better than chemotherapy alone.

Correspondence: Dr. E. Bajetta

E-mail to a Friend Email Physician More Information