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Melanoma treatment details. Chemotherapy. Immunotherapy. Tel Aviv-Sourasky Medical Center, Tel Aviv, Israel

Survival: 18.6 months
Toxicity Grade: 4
Treatments: Chemotherapy
Drugs: Platinol
Country: Israel
City/State/Province: Tel Aviv
Hospital: Tel Aviv-Sourasky Medical Center
Journal: Link
Date: 2/2006

Patients: This phase II study involved 23 patients with advanced inoperable melanoma, none of whom had been exposed to previous chemotherapy. Patients included 14 men and 9 women with the median age of 56 years.

Treatment: Treatment included a combination of chemotheray (cisplatin, vinblastine, and oral temozolomide) and immunotherapy (intravenous interleukin-2 and interferon-alfa).

Toxicity: Toxicities included: grade 3-4 myelosuppression and asthenia, and grade 3 neutropenic fever. Six patients had transient renal failure.

Results: Overall median survival was 18.6 momths.

Correspondence: Ilan Ron MD

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