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Ovarian Cancer treatment details. Chemotherapy. Institut Paoli-Calmettes, Marseille, France



Survival: 32.4 months
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
   
Drugs: Eloxatin
Taxol
Country: France
   
City/State/Province: Marseille
   
Hospital: Institut Paoli-Calmettes
   
Journal: Link
   
Date: 3/2006

Description:
Patients: This phase II study involved a total of 105 patients and 98 who were eligible for a response with advanced pretreated platinum-sensitive ovarian cancer. The median age was 58.

Treatments: Patients received chemotherapy - paclitaxel followed by oxaliplatin every 21 days for a maximum of 9 cycles.

Toxicity: Toxicities included: grade 4 neutropenia, thrombocytopenia and hyperbilirubinemia and grade 3 neurotoxicity. In fact, a total of 67% of patients experienced grade 3-4 neutropenia.

Results: The overall survival was reported as 32.4 months.

Support: The study was supported by Sanofi-Synthelabo. This company manufactures and/or markets oxaliplatin.

Correspodence: Dr. A. Yovine

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