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Colon Cancer treatment details. Chemotherapy. Universidad Autonoma de Madrid, Madrid, Spain



Survival: 13.2 months
   
Toxicity Grade: 5
   
Treatments: Chemotherapy
   
Drugs: Eloxatin
Xeloda
Country: Spain
   
City/State/Province: Madrid
   
Hospital: Universidad Autonoma de Madrid
   
Journal: Link
   
Date: 3/2006

Description:
Patients: This Phase II study involved 50 patients (36 men, 14 women, average age 76 years) with metastatic colorectal cancer. While one third of the patients had received adjuvant therapy before the study, none of the patients had been extensively treated. Metastatic sites included liver, lung, and lymph nodes.

Treatment: Treatment consisted of two chemotherapy agents: capecitabine and oxaliplatin.

Toxicity: There was one treatment related death from diarrhea and sepsis. in addition, grade 3-4 toxicities included diarrhea, asthenia, nausea, neutropenia, and thrombocytopenia.

Results: The median overall survival was 13.2 months.

Support: This study was supported by Roche Pharmaceuticals. Roche manufactures and/or markets capecitabine.

Correspondence: Dr. J. Feliu

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