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Colon Cancer treatment details. Chemotherapy. Hopital Huriez (CHRU), Lille, France

Survival: 18.7 months
Toxicity Grade: 4
Treatments: Chemotherapy
Drugs: Adrucil
Country: France
City/State/Province: Lille
Hospital: Hopital Huriez (CHRU)
Journal: Link
Date: 3/2006

Patients: This Phase II trial involved a total of 39 patients with metastatic colorectal cancer. For 29 patients the site of the primary tumor was in the colon. For 9 patients it was in the rectum. And for one patient, it was both. There were 23 men and 16 women. The median age was 64. Twenty-seven patients had a complete resection of the primary tumor and twelve had an incomplete resection.

Treatment: The treatment consisted of chemotherapy FOLFOX-6 (Oxaliplatin plus 5-FU and leucovorin (the active form of the B complex vitamin, folate) and FOLFIRI (Irinotecan plus 5-FU and leucovorin).

Toxicity: Grade 3-4 toxicities included neutropenia and diarrhea.

Results: The median overall survival was 18.7 months.

Correspondence: Mohamed Hebbar, MD

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