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Brain Cancer treatment details. Chemotherapy. Radiation. Institut Clinic de Malalties Hemato-Oncologique, Hospital Clinic, University of Barcelona, Barcelona, Spain



Survival: 7.6 months
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
Radiation
   
Drugs: Cytoxan
Paraplatin
Country: Spain
   
City/State/Province: Barcelona
   
Hospital: Institut Clinic de Malalties Hemato-Oncologique, Hospital Clinic, University of Barcelona
   
Journal: Link
   
Date: 2/2002

Description:
Patients: This Phase II study involved 17 patients with malignant glioma and large residual disease after surgery or biopsy. Fourteen patients had glioblastoma multiforme and 3 patients had anaplastic astrocytoma.

Treatment: The treatment consisted of chemotherapy drugs - carboplatin (paraplatin) and cyclophosphamide (cytoxan) followed by radiotherapy.

Toxicity: Toxicities included hematologic (grade 4), mucositis (grade 3), and neurotoxicity (grade 2).

Results: Median survival for all patients was 7.6 months.

Correspondence: N. Vinolas, MD

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