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Breast Cancer treatment details. Chemotherapy. Metaxa Cancer Hospital, Athens, Greece

Survival: 12.0 months
Toxicity Grade: 5
Treatments: Chemotherapy
Country: Greece
City/State/Province: Athens
Hospital: Metaxa Cancer Hospital
Journal: Link
Date: 10/2007

Patients: This phase II study involved 71 women with metastatic breast cancer. They all had disease progression after being treated with anthracycline-based therapy. The median age was 55, ranging from 28 to 72 years. The majority (61%) were post-menopausal.

Treatment: Patients were treated with the chemotherapy drugs docetaxel and ifosfamide.

Toxicity: One patient died from liver failure and encephalopathy. She had multiple liver metastases. Leukopenia, neutropenia, and anemia were the most common grade 3 and 4 toxicities. There was one grade 4 neurological/CNS toxicity reported. Other toxicities included thrombocytopenia (grade 2 and lower), nausea and vomiting, alopecia, mucositis, and diarrhea.

Results: The median overall survival was 12 months.

Correspondence: Dr. Christos Kosmas

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