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Lung Cancer treatment details. Chemotherapy. Memorial Sloan-Kettering Cancer Center, New York, NY, United States

Survival: 11.0 months
Toxicity Grade: 4
Treatments: Chemotherapy
Country: United States
City/State/Province: New York, NY
Hospital: Memorial Sloan-Kettering Cancer Center
Journal: Link
Date: 2/2008

Patients: This study involved 40 patients with stage IV non-small cell lung cancer. There were similar numbers of women (21) and men (19). Their median age was 70, ranging from 43-84 years of age.

Treatment: Patients were treated with albumin-bound paclitaxel. This form of paclitaxel dissolves easier and is less likely to cause the immune system to overreact to it, thus reducing the need for antihistamine and corticosteroid treatments.

Toxicity: The most common grade 3 toxicity was neutropenia, leukopenia, sensory neuropathy, fatigue, and diarrhea. Grade 4 neutropenia was reported in 5% of patients.

Result: The median overall survival was 11 months.

Support: This research was supported by Abraxis BioScience, which markets this form of paclitaxel as ABRAXANEŽ.

Correspondence: Dr. Naiyer A. Rizvi

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