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Ovarian Cancer treatment details. Chemotherapy. Cleveland Clinic Foundation, Cleveland, OH, United States



Survival: N/R
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
   
Drugs:
Country: United States
   
City/State/Province: Cleveland, OH
   
Hospital: Cleveland Clinic Foundation
   
Journal: Link
   
Date: 12/2005

Description:
Patients: This Phase I/II study involved 17 women with relapsed ovarian or peritoneal cancer. None of the patients had prior radiotherapy, and all patients had at least one chemotherapy treatment. The median age was 60 years.

Treatment: Treatment consisted of two chemotherapeutic agent: topotecan and carboplatin.

Toxicity: Grade 3-4 toxicities included allergy, neutropenia, anemia, leukopenia, and thrombocytopenia.

Results: The median overall survival was not reported. Thirteen patients responded to treatment, including four patients with a complete response.

Support: Glaxo SmithKline provided financial support for this study. Glaso Smith Kline manufactures and markets topotecan.

Correspondence: Peter G. Rose

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