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Ovarian Cancer treatment details. Chemotherapy. Catholic University, Campobasso, Campobasso, Italy



Survival: 12.9 months
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
   
Drugs:
Country: Italy
   
City/State/Province: Campobasso
   
Hospital: Catholic University, Campobasso
   
Journal: Link
   
Date: 2/2008

Description:
Patients: This phase III trial involved 153 women with recurrent or progressive ovarian cancer. The median age was 63 years old, ranging from 28 to 80.

Treatment: The women were treated with either gemcitabine or pegylated liposomal doxorubicin. Both of these are chemotherapy drugs.

Toxicity: Grade 3/4 neutropenia was reported in 16 patients treated with gemcitabine and 5 patients treated with doxorubicin. Grade 3 or 4 anemia, thrombocytopenia, fatigue, nausea, diarrhea, mucositis, and allergic reaction occurred in up to 6% of patients.

Results: The median overall survival was 12.9 months (56 weeks) in patients treated with pegylated liposomal doxorubicin, and 11.7 months (51 weeks) in those treated with gemcitabine.

Correspondence: Dr. Gabriella Ferrandina

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