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Prostate Cancer treatment details. Chemotherapy. Immunotherapy. Division of Medical Oncology, Azienda, Livorno, Italy

Survival: 19.2 months
Toxicity Grade: 4
Treatments: Chemotherapy
Country: Italy
City/State/Province: Livorno
Hospital: Division of Medical Oncology, Azienda
Journal: Link
Date: 12/2007

Patients: This phase II study involved 40 men with hormone refractory prostate cancer. The median age was 72, ranging from 55-83 years old.

Treatment: These patients were treated with docetaxel and estramustine, then most of them (27 of the 40 patients) were also given mitoxantrone and prednisone.

Toxicity: Grade 3/ 4 neutropenia, liver toxicity, deep vein thrombosis, and stomatitis were reported. The most common of these was liver toxicity, reported in 17.5% of patients.

Results: The median overall survival was 19.2 months.

Correspondence: Dr. Andrea Fontana

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