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Brain Cancer treatment details. Biologic therapy. Royal North Shore Hospital, University of Sydney, Sydney, Australia



Survival: 7.2 months
   
Toxicity Grade: 3
   
Treatments: Biologic therapy
   
Drugs: Thalomid
Country: Australia
   
City/State/Province: Sydney
   
Hospital: Royal North Shore Hospital, University of Sydney
   
Journal: Link
   
Date: 8/2001

Description:
Patients: Forty-two patients with recurrent glioblastoma multiforme were enrolled in this Phase II study.

Treatment: Treatment consisted of the administration of the anti-angiogenesis drug, thalidomide.

Toxicity: Toxicities included fatigue (grade 1-3), constipation (grade 1-3), rash (grade 1-3), xerostomia (1-3), oedema (grade 1-2), diarrhea (grade 2), and nausea/vomiting (grade 1-2).

Results: Median survival was 31 weeks (7.2 months).

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