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Breast Cancer treatment details. Chemotherapy. Applied Cancer Research-Institution for Translational Research Vienna , Vienna, Austria

Survival: 12.0 months
Toxicity Grade: 5
Treatments: Chemotherapy
Country: Austria
City/State/Province: Vienna
Hospital: Applied Cancer Research-Institution for Translational Research Vienna
Journal: Link
Date: 2/2008

Patients: This phase II study involved eighty-seven women with metastatic breast cancer. The majority had received chemotherapy and/or hormonal therapy.

Treatment: Patients were treated with the chemotherapy drug docetaxel.

Toxicity: One patient, with neutropenic fever, died of hemorrhage (intravascular coagulation, thrombocytopenia, internal bleeding, with pulmonary edema and liver disease). Neutropenia was the most common grade 4 toxicity, occurring in 87% of patients. Grade 4 leukopenia was reported in 48% of patients. Other toxicities included anemia, thrombocytopenia, nail disorder, asthenia, fluid retention, and pain.

Results: The median overall survival was 12 months.

Correspondence: Dr. Christian Dittrich

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