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Brain Cancer treatment details. Chemotherapy. University of California at San Francisco, San Francisco, California, United States



Survival: 7.9 months
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
   
Drugs: BCNU, BiCNU
Temodar
Country: United States
   
City/State/Province: San Francisco, California
   
Hospital: University of California at San Francisco
   
Journal: Link
   
Date: 1/2004

Description:
Patients: This Phase II study involved 36 adult patients with recurrent glioblastoma multiforme and 2 patients with gliosarcoma.

Treatment: Treatment consisted of two chemotherapy drugs BCNU and temozolomide (temodar).

Toxicity: Toxicities included: anemia (grade 3-4), constipation (grade 3), elevated liver enzymes (grade 3), fatigue (grade 3), granulocytopenia (grade 3-4), neutropenic infection (grade 4), non-neutropenic infection (grade 3), leucopenia (grade 3-4), lymphocytopenia (grade 3), thrombocytopenia (grade 3-4).

Results: Median survival was 34 weeks (7.9 months).

Correspondence: Michael Prados, MD

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