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Liver Cancer treatment details. Chemotherapy. Radiation. Qilu Hospital, Shandong University, Jinan, China



Survival: 37.0 months
   
Toxicity Grade: 5
   
Treatments: Chemotherapy
Radiation
   
Drugs:
Country: China
   
City/State/Province: Jinan
   
Hospital: Qilu Hospital, Shandong University
   
Journal: Link
   
Date: 4/2008

Description:
Patients: This study involved 291 patients with hepatocellular carcinoma (liver cancer). The majority of patients were men, and the average age of these patients was 63 years old.

Treatment: Patients were treated with transarterial chemoemobolization (TACE) and radiofrequency ablation (RFA) or TACE alone or RFA alone. TACE is a chemotherapy-delivery method, where cisplatin and lipiodol are given during a surgical procedure. RFA is radiation treatment.

Toxicity: Five deaths occurred that were related to treatment. Three of these patients died of liver failure, one patient died from a rupture of a vein in the esophagus (a esophagogastric varice), and one patient died from gastrointestinal bleeding. The most common toxicities were fever and pain.

Results: The median overall survival of patients treated with the transarterial chemoemobilization and radiofrequency ablation (TACE-RFA) was 37 months. The median overall survival of patients treated with TACE alone was 24 months, and for those treated with RFA only, the median overall survival was 22 months.

Correspondence: Dr. Bao-Quan Cheng

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