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Brain Cancer treatment details. Chemotherapy. Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan

Survival: ?
Toxicity Grade:
Treatments: Chemotherapy
Drugs: FUDR
Country: Japan
City/State/Province: Osaka
Hospital: Osaka Medical Center for Cancer and Cardiovascular Diseases
Journal: Link
Date: 6/2001

Patients: There were a total of 13 patients in this study comprised of six patients with glioblastoma, one patient with anaplastic astrocytoma and six patients with other metastatic brain tumors.

Treatment: Treatment consisted of intracavitary chemotherapy with 5-fluoro-2'-deoxyuridine (FdUrd, FUDR). (Two patients also received radiotherapy.) FdUrd is a 5-fluorouracil (5-FU) derivative.

Toxicity: No side effects such as nausea, vomiting, headache, convulsive attack or bone marrow suppression were observed in any of the patients.

Results: The overall response rate was 46.2%. Survival was not discussed.

Correspondence: H. Nakagawa, MD

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