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Ovarian Cancer treatment details. Biologic therapy. Chemotherapy. University of Queensland, Brisbane, Australia

Survival: 37.0 months
Toxicity Grade: 4
Treatments: Biologic therapy
Country: Australia
City/State/Province: Brisbane
Hospital: University of Queensland
Journal: Link
Date: 5/2008

Patients: This phase Ib study involved 48 women with epithelial ovarian, fallopian tube, or primary peritoneal cancer. They ranged in age from 32.4 to 68.7 years of age.

Treatment: Patients were treated with the chemotherapy drugs docetaxel and carboplatin, and the biological therapy erlotinib.

Toxicities: The most common grade 3 and grade 4 toxicities were vomiting, dehydration, rash, fatigue, oesophagitis, and neutropenia.

Results: The median overall survival was 37 months.

Sponsor: This study was supported by Hoffmann-La Roche Ltd. And Sanofi-Aventis Inc.

Correspondence: Dr. P.A. Vasey

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