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Ovarian Cancer treatment details. Chemotherapy. Wayne State University School of Medicine, Detroit, MI, United States



Survival: 21.2 months
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
   
Drugs:
Country: United States
   
City/State/Province: Detroit, MI
   
Hospital: Wayne State University School of Medicine
   
Journal: Link
   
Date: 6/2008

Description:
Patients: This phase II study involved 41 women with ovarian or peritoneal cancer. The majority (88%) had stage III/IV ovarian cancer. The median age was 62, ranging from 42 to 82 years of age.

Treatment: Patients were treated with the chemotherapy drug topotecan.

Toxicities: Grade 4 neutropenia was reported in one patient. Grade 3 thrombocytopenia, leukopenia, and anemia were reported. Grade 3 or 4 fatigue and dyspnea were also reported.

Results: The median overall survival was 21.2 months.

Sponsor: This study was supported by GlaxoSmithKline, which markets topotecan as Hycamtin“.

Correspondence: Dr. Robert Morris

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