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Brain Cancer treatment details. Immunotherapy. Osaka University Graduate School of Medicine, Osaka, Japan

Survival: 8.4 months
Toxicity Grade: 2
Treatments: Immunotherapy
Country: Japan
City/State/Province: Osaka
Hospital: Osaka University Graduate School of Medicine
Journal: Link
Date: 5/2008

Patients:  This phase II study involved 21 patients (7 women and 14 men) with recurrent glioblastoma multiforme.  They ranged in age from 20 to 76 years old.
Treatment:  Patients were given a vaccine (immunological therapy) designed to make their immune system destroy tumor cells. 

Toxicities:  There were not any grade 3 or 4 toxicities.  All patients had a local inflammatory response with erythema at the site where the vaccine was injected. 

Results:  The median overall survival after the initial vaccination was 36.7 weeks.  The median overall survival after tumor recurrence in the vaccinated patients was 46 weeks. 

Correspondence:  Dr. Shuichi Izumoto

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