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Ovarian Cancer treatment details. Chemotherapy. MD Anderson Cancer Center, Houston, TX, United States

Survival: 15.0 months
Toxicity Grade: 4
Treatments: Chemotherapy
Country: United States
City/State/Province: Houston, TX
Hospital: MD Anderson Cancer Center
Journal: Link
Date: 6/2008

Patients: This phase II study involved 26 women with recurrent or persistent epithelial ovarian or primary peritoneal cancer. The majority (16) were between the aged of 60 and 79 years of age.

Treatments: Patients were treated with the chemotherapy drug karenitecin.

Toxicity: Grade 3 or 4 neutropenia, leukopenia, thrombocytopenia and anemia were reported. Grade 3 gastrointestinal, metabolic, neurological, and ocular toxicities were also reported.

Results: The median survival was estimated to be 15 months.

Support: This study was supported by BioNumeric, Inc., which developed Karenitecin (BNP1350).

Correspondence: Dr. John Kavanagh

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