Cancer Treatment Results  Survival Rates Cancer Treatments / Therapy Results

Click here to go back to your search results.

Mesothelioma Cancer treatment details. Chemotherapy. H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, United States

Survival: 26.8 months
Toxicity Grade: 5
Treatments: Chemotherapy
Drugs: Pemetrexed
Country: United States
City/State/Province: Tampa, FL
Hospital: H. Lee Moffitt Cancer Center and Research Institute
Journal: Link
Date: 7/2008

Patients: This phase II study involved 20 patients with pleural mesothelioma. The majority (75%) were male. Their median age was 67.5, ranging from 46 to 79 years of age.

Treatment: Patients were treated with the chemotherapy drugs pemetrexed and gemcitabine.

Toxicity: One patient died from multiple organ failure related to treatment with the study drugs. The most frequently reported grade 3 and 4 toxicities were neutropenia (occurring in 60% of patients), febrile neutropenia (reported in 10% of patients), and anemia (reported in 1 patient). Other grade 3 and 4 toxicities were fatigue, dehydration, constipation, vomiting, diarrhea, dyspnea, and nausea.

Results: The median overall survival was 26.8 months.

Support: This study was supported by research funds from Eli Lilly & Co., which markets gemcitabine as GemzarŅ and pemetrexed as AlimtaŅ.

Correspondence: Dr. George R. Simon

E-mail to a Friend Email Physician More Information