Cancer Treatment Results  Survival Rates Cancer Treatments / Therapy Results

Click here to go back to your search results.

Brain Cancer treatment details. Chemotherapy. Radiation. Istituto Nazionale Neurologico Carlo Besta, Milan, Italy

Survival: 18.6 months
Toxicity Grade: 4
Treatments: Chemotherapy
Drugs: BCNU, BiCNU
Country: Italy
City/State/Province: Milan
Hospital: Istituto Nazionale Neurologico Carlo Besta
Journal: Link
Date: 12/2002

Patients: This study involved 30 newly diagnosed patients with glioblastoma. The patients were divided into two groups (A and B) of 15 patients each.

Treatment: Patients in Group A received intraarterial chemotherapy consisting of carboplatin (paraplatin) plus ACNU. Patients in Group B received intravenous chemotherapy consisting of cisplatin (platinol) plus BCNU. After the second course of chemotherapy and before the third cycle, all patients received radiotherapy.

Toxicity: For group B, grade 3 and 4 leukopenia occurred in 9 patients and 4 patients respectively. Grade 3 and 4 thrombocytopenia occurred in 7 and 2 patients respectively. One patient experienced focal seizures several hours after the end of treatment. One patient developed grade 3 anemia.

Results: Median survival time was 18.6 months (group B).

E-mail to a Friend More Information