Cancer Treatment Results  Survival Rates Cancer Treatments / Therapy Results
Cancer
 

Click here to go back to your search results.

Mesothelioma Cancer treatment details. Biologic therapy. Surgery. New York University School of Medicine, New York, NY, United States



Survival: 23.0 months
   
Toxicity Grade: 3
   
Treatments: Biologic therapy
Surgery
   
Drugs:
Country: United States
   
City/State/Province: New York, NY
   
Hospital: New York University School of Medicine
   
Journal: Link
   
Date: 8/2008

Description:
Patients: This phase II study involved 30 patients with malignant pleural mesothelioma. The average age was 66, ranging from 49 to 84 years of age. There were 25 men and 5 women.

Treatment: Patients had surgery and were treated with Tetrathiomolybdate. This is a biological therapy that affects copper levels and the development of new blood vessels (angiogenesis).

Toxicity: Many patients (53%) felt dizzy, but the dizziness was not related to any changes in blood pressure. Most (90%) of the patients reported grade 1 or 2 fatigue. Grade 3 granulocytopenia, anemia, and thrombocytopenia were also reported. The most common grade 3 toxicity was granulocytopenia, reported in 40% of the patients.

Results: The median overall survival was 23 months. For patients with stage I and II disease, the median survival time was 41 months, and for those with stage III disease, it was 15 months.

Support: This study was supported in part by funds from Attenuon LLC, a company which liscened the drug used in this study from the University of Michigan.

Correspondence: Dr. Harvey Pass

E-mail to a Friend Email Physician More Information