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Brain Cancer treatment details. Immunotherapy. Cedars-Sinai Medical Center, Los Angeles, CA, United States



Survival: 21.1 months
   
Toxicity Grade:
   
Treatments: Immunotherapy
   
Drugs:
Country: United States
   
City/State/Province: Los Angeles, CA
   
Hospital: Cedars-Sinai Medical Center
   
Journal: Link
   
Date: 7/2008

Description:
Patients: This phase 2 study involved 34 patients with glioblastoma multiforme. There were 10 women and 24 men, ranging in age from 22 to 74 years.

Treatment: Patients were treated with an immunotherapy, a vaccine against the tumor made from dendritic cells.

Toxicity: No toxicities associated with the treatment were reported.

Results: The median overall survival in patients that responded to the vaccine was 21.2 months (642 days), and 14.1 months (430) days in those that didnít respond (make a measureable immune response).

Support: This study was supported by research funds from MGI pharma, which developed the immunotherapy used in the study.

Correspondence: Dr. Christopher Wheeler

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