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Breast Cancer treatment details. Biologic therapy. Chemotherapy. Regina Elena National Cancer Institute, Rome, Italy



Survival: 17.8 months
   
Toxicity Grade: 3
   
Treatments: Biologic therapy
Chemotherapy
   
Drugs:
Country: Italy
   
City/State/Province: Rome
   
Hospital: Regina Elena National Cancer Institute
   
Journal: Link
   
Date: 9/2008

Description:
Patients: This phase II study involved 42 women with previously treated metastatic breast cancer. The median age was 57, ranging from 33 to 82 years old.

Treatment: Patients were treated with the chemotherapy drug capecitabine and the biological therapy celecoxib. Celecoxib is an inhibitor of COX-2.

Toxicity: Five grade 3 toxicities were reported: hand-foot syndrome, mucositis, nail changes, neutropenia, and anemia. Grade 1 and 2 toxicities included anemia, neutropenia, nausea/vomiting, hand-foot syndrome, heartburn, and fatigue.

Results: The median overall survival was 17.8 months.

Correspondence: Dr. Michele Milella

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