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Kidney Cancer treatment details. Chemotherapy. Sidney Kimmel Comprehensive Cancer Center of Johns Hopkins, Baltimore, MD, United States

Survival: 11.1 months
Toxicity Grade: 4
Treatments: Chemotherapy
Country: United States
City/State/Province: Baltimore, MD
Hospital: Sidney Kimmel Comprehensive Cancer Center of Johns Hopkins
Journal: Link
Date: 10/2008

Patients: This phase 2 study involved 25 patients with metastatic kidney cancer (renal cell carcinoma). There were 13 men and 12 women, with a median age of 60 years. These patients ranged in age from 50 to 80 years old. Most (84%) had previously been treated with surgery.

Treatment: Patients were treated with the chemotherapy drugs capecitabine and docetaxel.

Toxicity: Grade 4 anemia occurred in one patient. Grade 3 toxicities were reported in 10 of the patients, and included dehydration and diarrhea.

Results: The median overall survival was 11.1 months.

Support: This study was supported in part by research funds from Sanofi-Aventis, Inc., which markets docetaxel as TaxotereŽ.

Correspondence: Dr. Shanthi Marur

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