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Breast Cancer treatment details. Chemotherapy. University of Texas MD Anderson Cancer Center, Houston, TX, United States

Survival: 11.6 months
Toxicity Grade: 4
Treatments: Chemotherapy
Country: United States
City/State/Province: Houston, TX
Hospital: University of Texas MD Anderson Cancer Center
Journal: Link
Date: 11/2008

Patients: This phase 2 study involved 50 women with metastatic breast cancer. The median age was 50, ranging from 26 to 73 years of age.

Treatment: Patients were treated with the chemotherapy drugs gemcitabine and irinotecan.

Toxicity: Grade 4 neutropenia was reported in four patients, and grade 4 leukopenia was reported in one. Grade 3 toxicities included decreased hemoglobin, leucopenia, lymphopenia, neutropenia, low platelet count, fatigue, diarrhea and nausea.

Results: The median overall survival was 11.6 months.

Support: This study was supported in part by funds from Pfizer, which markets irinotecan as CAMPTOSAR.

Correspondence: Dr. Stacy Moulder

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