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Brain Cancer treatment details. Chemotherapy. Norris Cotton Cancer Center, Lebanon, NH, United States



Survival: 10.2 months
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
   
Drugs:
Country: United States
   
City/State/Province: Lebanon, NH
   
Hospital: Norris Cotton Cancer Center
   
Journal: Link
   
Date: 11/2008

Description:
Patients: This phase 2 study involved twenty-six patients with glioblastoma multiforme. Their median age was 55, ranging from 30 to 75.

Treatment: Patients were treated with the chemotherapy drugs thalidomide and irinotecan.

Toxicity: Grade 4 neutropenia and pulmonary embolism were each reported in one patient. Grade 3 toxicities included neutropenia, nausea, constipation, deep vein thrombosis, seizures, hyperglycemia, pain and neurologic deterioration.

Results: The median overall survival was 10.2 months.

Correspondence: Dr. Camilo E. Fadul

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