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Ovarian Cancer treatment details. Chemotherapy. University of Texas Southwestern Medical Center, Dallas, TX, United States



Survival: 11.4 months
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
   
Drugs: Pemetrexed
Country: United States
   
City/State/Province: Dallas, TX
   
Hospital: University of Texas Southwestern Medical Center
   
Journal: Link
   
Date: 3/2009

Description:
Patients: This phase 2 study involved fifty-one women with recurrent or persistent platinum-resistant ovarian or primary peritoneal cancer. The majority were between the ages of 40 and 79.

Treatment: These patients were treated with pemetrexed, a chemotherapy drug.

Toxicity: Grade 4 toxicities included leucopenia, thrombocytopenia, neutropenia, neurological and pain. Other toxicities (grade 3 and milder) included leucopenia, thrombocytopenia, neutropenia, anemia, gastrointestinal, nausea/vomiting, skin changes, neurological, metabolic changes, and infection.

Results: The median overall survival was 11.4 months.

Correspondence: Dr. David Scott Miller

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