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Lung Cancer treatment details. Biologic therapy. Chemotherapy. Toyohashi Municipal Hospital, Toyohashi, Aichi, Japan



Survival: 15.9 months
   
Toxicity Grade: 4
   
Treatments: Biologic therapy
Chemotherapy
   
Drugs:
Country: Japan
   
City/State/Province: Toyohashi, Aichi
   
Hospital: Toyohashi Municipal Hospital
   
Journal: Link
   
Date: 1/2009

Description:
Patients: This phase 2 study involved forty-four patients with stage IIIB or IV non-small cell lung cancer. The majority (31) were men. The median age was 64, ranging from 34 to 75 years of age.

Treatment: Patients were treated with the chemotherapy drugs carboplatin and paclitaxel and the biological therapy meloxicam. Meloxicam is a selective COX-2 inhibitor.

Toxicity: Grade 4 neutropenia and gastrointestinal tract perforation were reported, in three and one patients, respectively. Grade 3 toxicities were leucopenia, neutropenia, thrombocytopenia, anemia and nausea.

Results: The median overall survival was 15.9 months.

Correspondence: Dr. Ryujiro Suzuki

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