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Brain Cancer treatment details. Chemotherapy. Hopital Europeen Georges Pompidou, Paris, France

Survival: 3.5 months
Toxicity Grade: 4
Treatments: Chemotherapy
Country: France
City/State/Province: Paris
Hospital: Hopital Europeen Georges Pompidou
Journal: Link
Date: 5/2003

Patients: This multicentre Phase II trial involved 14 patients with recuurent glioblastoma multiforme. (14 patients were assessable for tumor response. 15 patients were assessable for toxicity.)

Treatment: Treatment consisted of the drugs lonidamine and diazepam.

Toxicity: The only grade 3 toxicity was somnolence. Other toxicities (2 or less) included: asthenia, muscular pain, and testicular pain.

Results: No complete or partial responses were observed. Median overall survival was 15 weeks (3.5 months).

Correspondence: Stephane Oudard, MD

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