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Breast Cancer treatment details. Biologic therapy. Chemotherapy. Tohoku University School of Medicine, Aoba-ku, Sendai, Japan



Survival: 22.3 months
   
Toxicity Grade: 3
   
Treatments: Biologic therapy
Chemotherapy
   
Drugs:
Country: Japan
   
City/State/Province: Aoba-ku, Sendai
   
Hospital: Tohoku University School of Medicine
   
Journal: Link
   
Date: 7/2009

Description:
Patients: This phase 2 study involved 38 women with metastatic breast cancer. The median age was 53, ranging from 30 to 69 years. Most of them (68.4%) were post-menopausal.

Treatment: Patients were treated with the biological therapy trastuzumab and the chemotherapy drug capecitabine.

Toxicity: Neutropenia was reported in 19 patients. Two patients had grade 3 neutropenia, and the others were grade 1 or 2. Three patients had grade 3 hand-foot syndrome and there was one report each of grade 3 vomiting and diarrhea.

Results: The median overall survival was 22.3 months.

Correspondence: Dr. Noriaki Ohuchi

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