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Melanoma treatment details. Immunotherapy. Ludwig Insitute for Cancer Research, Austin Hospital, Heidelberg, Victoria, Australia



Survival: 9.2 months
   
Toxicity Grade: 3
   
Treatments: Immunotherapy
   
Drugs:
Country: Australia
   
City/State/Province: Heidelberg, Victoria
   
Hospital: Ludwig Insitute for Cancer Research, Austin Hospital
   
Journal: Link
   
Date: 3/2009

Description:
Patients: This study involved 24 people with stage IV malignant melanoma. They had not previously received treatment for their cancer. There were 14 men and 10 women in this study. Their median age was 54.5, ranging from 25 to 67 years of age.

Treatment: Patients were treated with an immunotherapy, interleukin-21.

Toxicity: No grade 4 or 5 toxicities were reported. The most common grade 3 toxicity was leucopenia (low number of lymphocytes), which was reported in about 70% of patients. The most common grade 1 and 2 toxicities were abnormal laboratory tests (which returned to normal when the therapy was not being given), rash, pyrexia (fever), fatigue, headache, nausea, flu-like illness, leucopenia, and low platelets.

Results: The median overall survival was 9.2 months.

Correspondence: Dr. Ian Davis

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