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Rectal Cancer treatment details. Chemotherapy. Public Assistance Hospital of Paris, Paul Brousse Hospital, Villejuif, France

Survival: 18.0 months
Toxicity Grade: 4
Treatments: Chemotherapy
Country: France
City/State/Province: Villejuif
Hospital: Public Assistance Hospital of Paris, Paul Brousse Hospital
Journal: Link
Date: 7/2009

Patients: This study involved 29 patients with metastatic colorectal cancer. They had all received prior treatment for their cancer. Their median age was 62.5, ranging from 35 to 75 years of age.

Treatment: These patients received the chemotherapy drugs fluorouracil with irinotecan and/or oxaliplatin. The drugs were delivered directly to the liver, through a procedure called hepatic arterial infusion.

Toxicity: The most common grade 3 or 4 toxicity was abdominal pain, which was reported in 13.8% of the patients. Other grade 3 or 4 toxicities were fatigue, diarrhea, sensory neuropathy and neutropenia.

Results: The median overall survival was 18 months.

Support: This study was supported in part by Merck

Correspondence: Dr. Mohamed Bouchahda

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