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Rectal Cancer treatment details. Chemotherapy. Public Assistance Hospital of Paris, Paul Brousse Hospital, Villejuif, France



Survival: 18.0 months
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
   
Drugs:
Country: France
   
City/State/Province: Villejuif
   
Hospital: Public Assistance Hospital of Paris, Paul Brousse Hospital
   
Journal: Link
   
Date: 7/2009

Description:
Patients: This study involved 29 patients with metastatic colorectal cancer. They had all received prior treatment for their cancer. Their median age was 62.5, ranging from 35 to 75 years of age.

Treatment: These patients received the chemotherapy drugs fluorouracil with irinotecan and/or oxaliplatin. The drugs were delivered directly to the liver, through a procedure called hepatic arterial infusion.

Toxicity: The most common grade 3 or 4 toxicity was abdominal pain, which was reported in 13.8% of the patients. Other grade 3 or 4 toxicities were fatigue, diarrhea, sensory neuropathy and neutropenia.

Results: The median overall survival was 18 months.

Support: This study was supported in part by Merck

Correspondence: Dr. Mohamed Bouchahda

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