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Prostate Cancer treatment details. Biologic therapy. Chemotherapy. University of Pisa, Pisa, Italy



Survival: 21.0 months
   
Toxicity Grade: 2
   
Treatments: Biologic therapy
Chemotherapy
   
Drugs:
Country: Italy
   
City/State/Province: Pisa
   
Hospital: University of Pisa
   
Journal: Link
   
Date: 8/2009

Description:
Patients: This phase 2 study involved 28 patients with metastatic, hormone-refractory prostate cancer. Most had received chemotherapy previously. The median age was 74.5, ranging from 54 to 91 years of age.

Treatment: Patients were treated with a combination of biological therapy and chemotherapy: cyclophosphamide, celecoxib, and dexamethasone

Toxicity: No grade 3 or 4 toxicities were reported. There was one report each of grade 2 neutropenia, thrombocytopenia, and anorexia. There were three reports of grade 2 anemia and four reports of grade 2 asthenia.

Results: The median overall survival was 21 months.

Correspondence: Dr. Guido Bocci

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