Cancer Treatment Results  Survival Rates Cancer Treatments / Therapy Results
Cancer
 
Brain Tumor (Astrocytomas)

The Cancer Monthly database currently has the results (survival, side effects, and more) for 100 recent therapies for glioblastoma multiforme and 22 recent therapies for anaplastic astrocytoma including: immunotherapy, gene therapy, biological therapy, radiation, surgery, chemotherapy, and hormone therapy.

Sign Up and See the Results Right Now



Introduction

According to the World Health Organization (WHO) there are four grades of brain tumors that are derived from astrocytes which are a type of neuroglial brain cell. These tumors are called astrocytomas. These various types of astrocytomas include:

Grade
Prognosis
Examples
I
Excellent prognosis
Juvenile pilocytic astrocytoma (JPA),
Pleiomorhic xanthroastrocytoma (PXA)
II
Prognosis variable
Astrocytoma
III
Poor prognosis
Anaplastic astrocytoma
IV
Aggressive tumor
Glioblastoma multiforme

Treatment

High grade astrocytomas such as Anaplastic astrocytoma and Glioblastoma multiforme infiltrate surrounding brain tissue and, therefore, complete surgical removal is usually not possible. These cancers are usually fatal although prolonged survival does occur in a small minority of patients.

Radiation after surgery prolongs survival for a few months. The roles of sterotaxic radiosurgery and interstital brachytherapy are uncertain. Sterotaxic radiosurgery is the administration of a highly focused dose of radiation. Examples of this include gamma knife. Interstital brachytherapy is the placement of radioactive material directly into the tumor. This approach is associated with necrosis (i.e. death) of normal brain tissue.

Chemotherapy is only marginally effective in the treatment of Anaplastic astrocytoma and Glioblastoma multiforme. Typical chemotherapy agents include carmustine (BCNU) and lomustine (CCNU).

Treatment Results

Today, there are some encouraging published results with immunotherapy and biologic therapies (i.e. radio-immunotherapy, retinoid therapy, and vitamin analogs). The Cancer Monthly database currently has the results (survival, side effects, etc.) for 100 recent therapies for glioblastoma multiforme and 22 recent therapies for anaplastic astrocytoma including: immunotherapy, gene therapy, biological therapy, radiation, surgery, chemotherapy, and hormone therapy.

Sign Up and See the Results Right Now

 

Source: Stephen M. Sangar and Mark A. Israel, Primary and Metastatic Tumors of the Nervous System, in HARRISON'S PRINCIPLES OF INTERNAL MEDICINE, pt. 15 § 358, at 2452-2460 (Dennis L. Kasper, M.D. et al., eds, 16th ed 2005).