Treatment Information

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Mesothelioma treatment details. Chemotherapy, Immunotherapy.

Center Hospitalier Intercommunal de Creteil, Creteil, France.

Survival: monthsCountry:France
Toxiciy Grade:3City/State/Province:Creteil
Treatments:Chemotherapy, ImmunotherapyHospital:Center Hospitalier Intercommunal de Creteil
Drugs:Journal:Link
Date:Jun 2002

Description:

Patients: This Phase II study involved 17 patients with Malignant Pleural Mesothelioma. Many of the patients had undergone “preventive radiotherapy.”

Treatment: The treatment consisted of a type of immunotherapy – administration of intrapleurally infused autologous human activated macrophages (a type of blood cell) followed by intrapleural injection of gamma-interferon (a type of protein). After completion of this therapy, ten patients were treated with chemotherapy (primarily cisplatin (platinol) and mitomycin (mitozytrex)).

Toxicity: Toxicities included grade 2 or 3 thoracic pain after injection, fever, and alkaline phosphatases.

Results: The median survival of all treated patients was 29.2 months.

Correspondence: Manuel Lopez, MD




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