Treatment Information

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Breast Cancer treatment details. Chemotherapy.

University General Hospital of Heraklion, Crete, Greece.

Survival: monthsCountry:Greece
Toxiciy Grade:4City/State/Province:Crete
Treatments:ChemotherapyHospital:University General Hospital of Heraklion
Drugs:Journal:Link
Date:Sep 2011

Description:

Patients:
This phase III study involved women with metastatic breast cancer who had previously received chemotherapy. These patients were divided into two separate treatment groups. Group A had 74 patients with a median age of 60 years. Group B also consisted of 74 patients with a median age of 60 years.

Treatment:
Group A was treated with a combination of the chemotherapy agents vinorelbine and gemcitabine. Group B was treated with the chemotherapy agent capecitabine.

Toxicities:
The most severe toxicities in group A were grade 4 neutropenia (5 patients). Grade 3 fatigue (3 patients) was also reported.

The most severe toxicities in group B were one case each of grade 4 neutropenia and allergy. Grade 3 hand-foot skin reaction (4 patients) was also reported.

Results:
The median overall survival for groups A and B was 20.4 and 22.4 months, respectively.

Correspondence: Dr. D. Mavroudis; email: [email protected]



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