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Prostate Cancer treatment details. Biologic therapy.

University of Athens School of Medicine, Athens, Greece.

Survival: monthsCountry:Greece
Toxiciy Grade:3City/State/Province:Athens
Treatments:Biologic therapyHospital:University of Athens School of Medicine
Drugs:Journal:Link
Date:Jan 2004

Description:

Patients: This Phase II study involved 38 patients with hormone refractory prostate cancer. Patients were divided into two groups: Group 1 and Group 2. The average age of patients in Group 2 was 74 and the median PSA was 103 .5 (range from 8.5 – 4290).

Treatment: Patients in Group 2 were treated with a somatostatin analogue (lanreotide, somatuline), dexamethasone and orchiectomy or the LHRH (lutenizing hormone-releasing hormone) analog triptorelin (arvekap).

Toxicity: For patients in Group 2, grade 2-3 toxicities included anemia, fluid retention, and elevated blood glucose.

Results: The median overall survival for patients in Group 2 was 18 months.

Correspondence: M.A. Dimopoulos, MD





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