Treatment Information

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Brain – Glioblastoma Multiforme treatment details. Chemotherapy.

Royal Melbourne Hospital, Victoria, Australia.

Survival: monthsCountry:Australia
Toxiciy Grade:3City/State/Province:Victoria
Treatments:ChemotherapyHospital:Royal Melbourne Hospital
Drugs:Journal:Link
Date:Nov 2011

Description:

Patients:
This phase II study involved 40 newly diagnosed glioblastoma multiforme (GBM) patients who had previously received radiation therapy. The median patient 53 years and 73% of the patients were male.

Treatment:
Patients were treated with the chemotherapy agents temozolomide and pegylated liposomal doxorubicin (PLD).

Toxicities:
The highest toxicity grade reported was grade 3 and included hand-foot skin reactions, neutropenia, and mucositis (inflammation of the GI tract lining).

Results:
The median overall survival was 13.4 months.

Support:
This study was partially supported by the pharmaceutical company Schering-Plough.

Correspondence: Dr. Sumitra Ananda; email: [email protected]



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