Treatment Information

Back

Liver Cancer treatment details. Biologic therapy.

Massachusetts General Hospital Cancer Center, Boston, MA, United States.

Survival: monthsCountry:United States
Toxiciy Grade:5City/State/Province:Boston, MA
Treatments:Biologic therapyHospital:Massachusetts General Hospital Cancer Center
Drugs:Journal:Link
Date:Dec 2013

Description:

Patients:
This phase 2 study involved 42 advanced hepatocellular cancer patients. The median patient age was 63 years and 81% were male.

Treatment:
Patients were treated with the biologic therapy agent called ramucirumab, a monoclonal antibody for the VEGF receptor 2 protein that inhibits cancer cell growth.

Toxicities:
There was one treatment-related death due to gastrointestinal hemorrhage. Grade 4 hypertension and grade 1 headache and nausea were also reported.

Results:
The median overall survival was 12.0 months.

Support:
This study was partially supported by ImClone Systems, which is owned by the pharmaceutical company Eli Lilly.

Correspondence: Dr. Andrew X. Zhu; email: [email protected]



Back