Treatment Information

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Brain – Glioblastoma Multiforme treatment details. Chemotherapy, Biologic therapy.

Duke University Medical Center, Durham, NC, United States.

Survival: monthsCountry:United States
Toxiciy Grade:5City/State/Province:Durham, NC
Treatments:Chemotherapy, Biologic therapyHospital:Duke University Medical Center
Drugs:Journal:Link
Date:Apr 2013

Description:

Patients:
This phase 2 study involved 41 unresectable glioblastoma patients who had not been previously treated. The median patient age was 59.1 years and 26 were male.

Treatment:
Patients were treated with the chemotherapy agent temozolomide and the biologic therapy agent bevacizumab.

Toxicities:
There was one treatment-related death due to heart attack. Grade 4 neutropenia, blood clot, and fatigue were also reported.

Results:
The median overall survival was 11.7 months.

Support:
This study was partially supported by Genentech Pharmaceuticals.

Correspondence: Dr. Emil Lou; email: [email protected]



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