|Toxiciy Grade:||5||City/State/Province:||Queens, New York|
|Treatments:||Surgery||Hospital:||Queens Hospital Center|
Patients: This trial involved patients with one to three potentially resectable metastases of colorectal carcinoma to the liver. There were a total of 75 “assessable” patients in this trial divided into two groups. The “Control” group contained 45 patients and the “Chemotherapy” group contained 30 patients.
Treatment: Treatment in the Control group involved surgery only. Treatment in the Chemotherapy group involved surgery plus postoperative hepatic arterial floxuridine combined with intravenous continuous-infusion fluorouracil.
Toxicity: There were two postoperative deaths from operative complications – one in each group.
Results: The median survival of the Control group was 49.4 months.
Correspondence: M. Margaret Kemeny, MD