Treatment Information

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Non-Hodgkin's Lymphoma treatment details. Chemotherapy, Radiation.

Memorial Sloan-Kettering Cancer Center, New York, NY, United States.

Survival: monthsCountry:United States
Toxiciy Grade:5City/State/Province:New York, NY
Treatments:Chemotherapy, RadiationHospital:Memorial Sloan-Kettering Cancer Center
Drugs:Journal:Link
Date:Nov 2013

Description:

Patients:
This phase 2 study involved 52 newly diagnosed primary central nervous system lymphoma patients. The median patient age was 60 years and 30 were male.

Treatment:
Patients were treated with a chemotherapy regimen of rituximab, methotrexate, procarbazine, vincristine, and cytarabine, and with radiation therapy.

Toxicities:
There were three treatment-related deaths due to neutropenia with fever. Grade 4 gastrointestinal perforation and grade 3 kidney toxicity were also reported.

Results:
The median overall survival was 79.2 months.

Support:
This study was partially supported by Genentech.

Correspondence: Dr. Antonio Omuro; email: omuroa@mskcc.org



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