Treatment Information

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Breast Cancer treatment details. Chemotherapy, Biologic therapy.

Albert Einstein Cancer Center, Bronx, NY, United States.

Survival: monthsCountry:United States
Toxiciy Grade:4City/State/Province:Bronx, NY
Treatments:Chemotherapy, Biologic therapyHospital:Albert Einstein Cancer Center
Drugs:Journal:Link
Date:Jul 2012

Description:

Patients:
This phase 2 study involved 63 female taxane-resistant metastatic breast cancer patients who had been previously treated with anthracyclines. The median patient age was 52 years.

Treatment:
Patients were treated with the chemotherapy agent capecitabine and the biologic therapy agent tipifarnib, which is an inhibitor of a protein called farnesyltransferase.

Toxicities:
The most severe toxicities were of grade 4 and included neutropenia, thrombocytopenia, and shortness of breath. Grade 3 nausea, vomiting, diarrhea, and anorexia were also reported.

Results:
The median overall survival was 11.4 months.

Correspondence: Dr. Tianhong Li; email: [email protected]



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